Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fever-induced life-threatening arrhythmias in children harboring an SCN5A mutation.

Pediatrics - 1 Jan 2011

Chockalingam Priya, Rammeloo Lukas A, Postema Pieter G, Hruda Jarda, Clur Sally-Ann B, Blom Nico A, Wilde Arthur A

Abstract excerpt

Cardiac channelopathies caused by SCN5A mutation are well tolerated by most patients. However, the dramatic presentation of a previously healthy 4-month-old girl with life-threatening arrhythmias and the subsequent findings in the child and her family provide evidence that loss-of-function sodium channel mutations can present very early in life. An SCN5A mutation was detected in the infant, her brother, and their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arrhythmias, Cardiac
Share to Cardiac electrophysiology and arrhythmias

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Infant

Share to Muscle Proteins

Share to Mutation

Share to NAV1.5 Voltage-Gated Sodium Channel

Share to Sodium Channels

Source

Identifiers

PMID: 21135007
DOI: 10.1542/peds.2010-1688

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fever-induced life-threatening arrhythmias in children harboring an SCN5A mutation.PMID 21135007Read ↗

Life-Threatening Ventricular Arrhythmia Induced by Atrial Tachycardia in a Child with an SCN5A Mutation.Semantic proximity Read ↗

A novel SCN5A mutation V1340I in Brugada syndrome augmenting arrhythmias during febrile illnessSemantic proximity Read ↗

Brugada syndrome and fever: genetic and molecular characterization of patients carrying SCN5A mutations.Semantic proximity Read ↗

A novel SCN5A mutation manifests as a malignant form of long QT syndrome with perinatal onset of tachycardia/bradycardia.Semantic proximity Read ↗

Cardiac channelopathies associated with infantile fatal ventricular arrhythmias: from the cradle to the bench.Semantic proximity Read ↗

A novel SCN5A arrhythmia mutation, M1766L, with expression defect rescued by mexiletineSemantic proximity Read ↗

Unique mixed phenotype and unexpected functional effect revealed by novel compound heterozygosity mutations involving SCN5A.Semantic proximity Read ↗

Absence of family history and phenotype-genotype correlation in pediatric Brugada syndrome: more burden to bear in clinical and genetic diagnosis.Semantic proximity Read ↗

A novel SCN5A mutation, F1344S, identified in a patient with Brugada syndrome and fever-induced ventricular fibrillationSemantic proximity Read ↗

Long QT syndrome due to a novel mutation in SCN5A: treatment with ICD placement at 1 month and left cardiac sympathetic denervation at 3 months of age.Semantic proximity Read ↗

In Children and Adolescents From Brugada Syndrome–Families, Only SCN5A Mutation Carriers Develop a Type-1 ECG Pattern Induced By FeverSemantic proximity Read ↗

Electrical storm in a patient with arrhythmogenic right ventricular cardiomyopathy and SCN5A mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.