Article
Cardiac channelopathies associated with infantile fatal ventricular arrhythmias: from the cradle to the bench.
Journal of cardiovascular electrophysiology - 1 Jan 2014
Kato Koichi, Makiyama Takeru, Wu Jie, Ding Wei-Guang, Kimura Hiromi, Naiki Nobu, Ohno Seiko, Itoh Hideki, Nakanishi Toshio, Matsuura Hiroshi, Horie Minoru
Abstract excerpt
BACKGROUND: Fatal ventricular arrhythmias in the early period of life have been associated with cardiac channelopathies for decades, and postmortem analyses in SIDS victims have provided evidence of this association. However, the prevalence and functional properties of cardiac ion channel mutations in infantile fatal arrhythmia cases are not clear. METHODS AND RESULTS: Seven infants with potentially lethal...
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