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Article

Brugada syndrome and fever: genetic and molecular characterization of patients carrying SCN5A mutations.

Cardiovascular research - 15 Aug 2005

Keller Dagmar I, Rougier Jean-Sébastien, Kucera Jan P, Benammar Nawal, Fressart Véronique, Guicheney Pascale, Madle Alois, Fromer Martin, Schläpfer Jürg, Abriel Hugues

Abstract excerpt

OBJECTIVE: Brugada syndrome (BrS) is characterized by ventricular tachyarrhythmias leading to sudden cardiac death and is caused, in part, by mutations in the SCN5A gene encoding the sodium channel Na(v)1.5. Fever can trigger or exacerbate the clinical manifestations of BrS. The aim of this work was to characterize the genetic and molecular determinants of fever-dependent BrS. METHODS: Four male patients with...

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Identifiers

PMID: 15890323
DOI: 10.1016/j.cardiores.2005.03.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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