In Children and Adolescents From Brugada Syndrome–Families, Only SCN5A Mutation Carriers Develop a Type-1 ECG Pattern Induced By Fever

Abstract excerpt

pediatrics retrospective studies B rugada syndrome (BrS) is a rare inherited condition in which ventricular arrhythmias may cause syncope, aborted cardiac arrest, or sudden cardiac death.Although BrS is associated with mutations in the SCN5A gene, most adult patients are SCN5A-mutation negative. 1Fever can unmask the diagnostic Brugada type-1 pattern on the ECG 2 and precede arrhythmic symptoms, especially in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cardiac electrophysiology and arrhythmias
• Share to ECG Monitoring and Analysis
• Share to Ion channel regulation and function