Article
Role of FOXA and Sp1 in mitochondrial acylcarnitine carrier gene expression in different cell lines.
Biochemical and biophysical research communications - 7 Jan 2011
Convertini Paolo, Infantino Vittoria, Bisaccia Faustino, Palmieri Ferdinando, Iacobazzi Vito
Abstract excerpt
This study investigates the transcriptional role of the human mitochondrial carnitine/acylcarnitine carrier (CAC) proximal promoter. Through deletion analysis, an activation domain (-334/-80 bp) was identified which contains FOXA and Sp1 active sites. The wild-type (but not mutated) -334/-80 bp r...
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