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Article

Pharmacological modulation of anxiety-like phenotypes in adult zebrafish behavioral models.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Aug 2011

Stewart Adam, Wu Nadine, Cachat Jonathan, Hart Peter, Gaikwad Siddharth, Wong Keith, Utterback Eli, Gilder Thomas, Kyzar Evan, Newman Alan, Carlos Dillon, Chang Katie, Hook Molly, Rhymes Catherine, Caffery Michael, Greenberg Mitchell, Zadina James, Kalueff Allan V

Abstract excerpt

Zebrafish (Danio rerio) are becoming increasingly popular in neurobehavioral research. Here, we summarize recent data on behavioral responses of adult zebrafish to a wide spectrum of putative anxiolytic and anxiogenic agents. Using the novel tank test as a sensitive and efficient behavioral assay, zebrafish anxiety-like behavior can be bi-directionally modulated by drugs affecting the gamma-aminobutyric acid,...

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PMID: 21122812
DOI: 10.1016/j.pnpbp.2010.11.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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