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Article

Modulation of Threat Response in Larval Zebrafish.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Rennekamp Andrew J

Abstract excerpt

High-throughput, whole-organism phenotypic drug screening is made possible using live zebrafish larvae. Many human drugs have now been shown to affect zebrafish larvae in similar ways, through homologous molecular mechanisms. At this stage in life, zebrafish are small enough to fit in multi-well, microliter plates, yet developed enough to exhibit complex phenotypes, such as hunting behaviors and avoidance of...

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PMID: 29736716
DOI: 10.1007/978-1-4939-7847-2_11

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