Article
Evaluating a newly developed pharmacogenetic array: screening in a Spanish population.
Pharmacogenomics - 1 Nov 2010
Almoguera Berta, Riveiro-Alvarez Rosa, Gomez-Dominguez Belen, Lopez-Rodriguez Rosario, Dorado Pedro, Vaquero-Lorenzo Concepción, Dal-Ré Rafael, Fernandez-Piqueras Jose, Llerena Adrián, Abad-Santos Francisco, Ayuso Carmen
Abstract excerpt
AIMS: How genes affect the response in a patient to a given medication is still poorly understood; the validation of biomarkers and technologies need to be performed. This study aims to determine the analytical characteristics of PHARMAChip(®), a newly developed pharmacogenetic array, and the Spanish population allelic and genotypic frequencies of the genetic variants included in this chip. MATERIALS & METHODS:...
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