Article
c-Kit expression and mutations in phyllodes tumors of the breast.
Anticancer research - 1 Nov 2010
Bose Prithviraj, Dunn S Terence, Yang Jian, Allen Richard, El-Khoury Christian, Tfayli Arafat
Abstract excerpt
BACKGROUND: Phyllodes tumors (PTs) represent uncommon fibroepithelial lesions of the breast that express c-Kit and platelet-derived growth factor receptor-alpha, similar to gastrointestinal stromal tumors (GISTs). 'Activating' mutations in these genes underlie responsiveness of GISTs to imatinib....
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