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Article

Interleukin-28B gene polymorphisms do not influence the susceptibility to HIV-infection or CD4 cell decline.

AIDS (London, England) - 14 Jan 2011

Rallon Norma I, Restrepo Clara, Naggie Susanna, Lopez Mariola, Del Romero Jorge, Goldstein David, McHutchison John, Soriano Vincent, Benito Jose M

Abstract excerpt

The critical role of interleukin-28B (IL28B)/interferon-λ3 (IFN-λ3) polymorphisms on the susceptibility to hepatitis C virus infection and the response to peginterferon-ribavirin therapy has encouraged exploration of similar effects on other viruses. Given that IFN-λ mediates anti-HIV-1 activity,...

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Identifiers

PMID: 21099665
DOI: 10.1097/QAD.0b013e328341b84e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21099665-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Interleukin-28B gene polymorphisms do not influence the susceptibility to HIV-infection or CD4 cell decline.PMID 21099665Read ↗

IL28B polymorphism does not determine outcomes of hepatitis B virus or HIV infection.Semantic proximity Read ↗

Interleukin 28B genetic polymorphism and hepatitis B virus infection.Semantic proximity Read ↗

Will IL28B polymorphism remain relevant in the era of direct-acting antiviral agents for hepatitis C virus?Semantic proximity Read ↗

Protective interleukin-28B genotype affects hepatitis C virus clearance, but does not contribute to HIV-1 control in a cohort of African-American elite controllers/suppressors.Semantic proximity Read ↗

Impact of IL28B gene polymorphisms on interferon-λ3 plasma levels during pegylated interferon-α/ribavirin therapy for chronic hepatitis C in patients coinfected with HIV.Semantic proximity Read ↗

Interleukin 28B rs12979860 genotype and Human Immunodeficiency Virus type 1: Susceptibility, AIDS development and therapeutic outcome.Semantic proximity Read ↗

Effect of Interleukin-28B polymorphism on Interleukin-28 expression and immunological recovery amongst HIV-1-infected individuals following antiretroviral therapy.Semantic proximity Read ↗

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Pharmacodynamics of PEG-IFN-[alpha]-2a and HCV response as a function of IL28B polymorphism in HIV/HCV-coinfected patients.Semantic proximity Read ↗

AIDS incidence and survival in a hospital-based cohort of HIV-positive patients from São Paulo, Brazil: The role of IFN-λ4 polymorphisms.Semantic proximity Read ↗

IFNL4 Genotype Does Not Associate with CD4 T-Cell Recovery in People Living with Human Immunodeficiency Virus.Semantic proximity Read ↗

IL28B genotype does not correlate with HIV control in African Americans.Semantic proximity Read ↗

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