Article
Identification of immunogenic consensus T-cell epitopes in globally distributed influenza-A H1N1 neuraminidase.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2011
Gupta Shishir K, Srivastava Mugdha, Akhoon Bashir A, Smita Suchi, Schmitz Ulf, Wolkenhauer Olaf, Vera Julio, Gupta Shailendra K
Abstract excerpt
Antigenic drift is the ability of the swine influenza virus to undergo continuous and progressive changes in response to the host immune system. These changes dictate influenza vaccine updates annually to ensure inclusion of antigens of the most current strains. The identification of those peptides that stimulate T-cell responses, termed T-cell epitopes, is essential for the development of successful vaccines. In...
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