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Article

Association between Caspase-9 promoter region polymorphisms and discogenic low back pain.

Connective tissue research - 1 Apr 2011

Guo Tuan-Mao, Liu Miao, Zhang Yin-Gang, Guo Wen-Tao, Wu Shi-Xun

Abstract excerpt

Caspase-9 (CASP-9) is an initiator caspase protease for apoptosis, and plays an important role in the development and progression of lumbar disc disease (LDD). The expression and/or activity of CASP-9 are significantly enhanced in the degenerated disc. The polymorphism in the promoter region of C...

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Identifiers

PMID: 21091209
DOI: 10.3109/03008207.2010.487621

Genes

LBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21091209-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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