Article
Frameshift and nonsense mutations in a human genomic sequence homologous to a murine UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase cDNA.
The Journal of biological chemistry - 25 Apr 1990
Larsen R D, Rivera-Marrero C A, Ernst L K, Cummings R D, Lowe J B
Abstract excerpt
We have previously isolated a murine UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase (alpha(1,3)-GT) cDNA (Larsen, R. D., Rajan, V. P., Ruff, M. M., Kukowska-Latallo, J., Cummings, R. D., and Lowe, J. B. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 8227-8231). This enzyme construc...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- DNA
- Galactosyltransferases
- Genes
- Genomic Library
- Humans
- Mice
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Restriction Mapping
- Sequence Homology, Nucleic Acid