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Article

A complete 1,3-galactosyltransferase gene is present in the human genome and partially transcribed

1 Dec 2002

Abstract excerpt

The synthesis of Galalpha1-3Gal-terminated oligosaccharides (alpha-Gal) epitopes has been interrupted during the course of evolution, starting with Old World primates. Partial sequences similar to the alpha1,3-galactosyltransferase (alpha1,3GalT) gene, which governs the synthesis of alpha-Gal epitopes, have been detected in the human genome and were found to correspond to pseudogenes. We completed the sequence of...

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PMID: 12499400
DOI: 10.1093/glycob/cwf087

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