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Article

Bidirectional transcription stimulates expansion and contraction of expanded (CTG)*(CAG) repeats.

Human molecular genetics - 1 Feb 2011

Nakamori Masayuki, Pearson Christopher E, Thornton Charles A

Abstract excerpt

More than 12 neurogenetic disorders are caused by unstable expansions of (CTG)•(CAG) repeats. The expanded repeats are unstable in germline and somatic cells, with potential consequences for disease severity. Previous studies have shown that contractions of (CAG)(95) are more frequent when the re...

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Identifiers

PMID: 21088112
DOI: 10.1093/hmg/ddq501
PMCID: PMC3016912

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21088112-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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