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Article

First example of hepatocyte transplantation to alleviate ornithine transcarbamylase deficiency, monitored by NMR-based metabonomics.

Bioanalysis - 1 Dec 2009

Legido-Quigley Cristina, Cloarec Olivier, Parker David A, Murphy Gerard M, Holmes Elaine, Lindon John C, Nicholson Jeremy K, Mitry Ragai R, Vilca-Melendez Hector, Rela Mohamed, Dhawan Anil, Heaton Nigel

Abstract excerpt

We demonstrate the effective use of NMR spectroscopic profiles of urine and plasma from the first successful use of hepatocyte transplantation as a bridge to auxiliary partial orthotopic liver transplantation in a child antenatally diagnosed with severe ornithine transcarbamylase deficiency. In t...

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Source

Identifiers

PMID: 21083101
DOI: 10.4155/bio.09.112

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21083101-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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