Article
Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans.
Hepatology (Baltimore, Md.) - 1 Oct 2014
Ladep Nimzing G, Dona Anthony C, Lewis Matthew R, Crossey Mary M E, Lemoine Maud, Okeke Edith, Shimakawa Yusuke, Duguru Mary, Njai Harr F, Fye Haddy K S, Taal Makie, Chetwood John, Kasstan Ben, Khan Shahid A, Garside Deborah A, Wijeyesekera Anisha, Thillainayagam Andrew V, Banwat Edmund, Thursz Mark R, Nicholson Jeremy K, Njie Ramou, Holmes Elaine, Taylor-Robinson Simon D
Abstract excerpt
UNLABELLED: There is no clinically applicable biomarker for surveillance of hepatocellular carcinoma (HCC), because the sensitivity of serum alpha-fetoprotein (AFP) is too low for this purpose. Here, we determined the diagnostic performance of a panel of urinary metabolites of HCC patients from West Africa. Urine samples were collected from Nigerian and Gambian patients recruited on the case-control platform of...
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