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Article

HIF pathway mutations and erythrocytosis.

Expert review of hematology - 1 Feb 2010

McMullin Mary Frances

Abstract excerpt

Erythrocytosis is present when there is an increase in the red cell mass, usually accompanied by an elevated hemoglobin and hematocrit. This occurs when there is an intrinsic defect in the erythroid component of the bone marrow or for secondary reasons when an increase in erythropoietin production drives red cell production. In normoxic conditions, HIF-α interacts with the other proteins in the HIF pathway and is...

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Source

Identifiers

PMID: 21082936
DOI: 10.1586/ehm.09.68

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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