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Article

Translation elongation factor 1A facilitates the assembly of the tombusvirus replicase and stimulates minus-strand synthesis.

PLoS pathogens - 4 Nov 2010

Li Zhenghe, Pogany Judit, Tupman Steven, Esposito Anthony M, Kinzy Terri Goss, Nagy Peter D

Abstract excerpt

Replication of plus-strand RNA viruses depends on host factors that are recruited into viral replicase complexes. Previous studies showed that eukaryotic translation elongation factor (eEF1A) is one of the resident host proteins in the highly purified tombusvirus replicase complex. Using a random...

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PMID: 21079685
DOI: 10.1371/journal.ppat.1001175
PMCID: PMC2973826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21079685-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Translation elongation factor 1A facilitates the assembly of the tombusvirus replicase and stimulates minus-strand synthesis.PMID 21079685Read ↗

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