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Article

Subversion of selective autophagy for the biogenesis of tombusvirus replication organelles inhibits autophagy

14 Mar 2024

Abstract excerpt

Elaborate viral replication organelles (VROs) are formed to support positive-strand RNA virus replication in infected cells. VRO formation requires subversion of intracellular membranes by viral replication proteins. Here, we showed that the key ATG8f autophagy protein and NBR1 selective autophagy receptor were co-opted by Tomato bushy stunt virus (TBSV) and the closely-related carnation Italian ringspot virus....

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PMID: 38484009
DOI: 10.1371/journal.ppat.1012085

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