Article

Elucidating Mechanisms of Antitumor Immunity Mediated by Live Oncolytic Vaccinia and Heat-Inactivated Vaccinia

2021-02-12

Abstract excerpt

<h4>Background</h4> Viral-based immunotherapy has the potential to overcome resistance to immune checkpoint blockade (ICB) and to fill the unmet needs of many cancer patients. Oncolytic viruses (OVs) are defined as engineered or naturally occurring viruses that selectively replicate in and kill cancer cells. OVs also induce antitumor immunity. The purpose of this study is to compare the antitumor effects of live...

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Literature Corpus work: 54f30228-f1e7-5fd6-9273-38f92c27647d
DOI: 10.1101/2021.02.11.427912

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