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Article

Resistance to juvenile hormone and an insect growth regulator in Drosophila is associated with an altered cytosolic juvenile hormone-binding protein.

Proceedings of the National Academy of Sciences of the United States of America - 1 Mar 1990

Shemshedini L, Wilson T G

Abstract excerpt

The Met mutant of Drosophila melanogaster is highly resistant to juvenile hormone III (JH III) or its chemical analog, methoprene, an insect growth regulator. Five major mechanisms of insecticide resistance were examined in Met and susceptible Met+ flies. These two strains showed only minor differences when penetration, excretion, tissue sequestration, or metabolism of [3H]JH III was measured. In contrast, when...

Topics

Adipose Tissue
Alleles
Animals
Carrier Proteins
Cytosol
Drosophila melanogaster
Genotype
Insect Proteins
Juvenile Hormones
Methoprene
Mutation

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Identifiers

PMID: 2107540
DOI: 10.1073/pnas.87.6.2072
PMCID: PMC53628

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2107540-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Resistance to juvenile hormone and an insect growth regulator in Drosophila is associated with an altered cytosolic juvenile hormone-binding protein.PMID 2107540Read ↗

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