Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resistance to juvenile hormone and an insect growth regulator in Drosophila is associated with an altered cytosolic juvenile hormone-binding protein.

Proceedings of the National Academy of Sciences of the United States of America - 1 Mar 1990

Shemshedini L, Wilson T G

Abstract excerpt

The Met mutant of Drosophila melanogaster is highly resistant to juvenile hormone III (JH III) or its chemical analog, methoprene, an insect growth regulator. Five major mechanisms of insecticide resistance were examined in Met and susceptible Met+ flies. These two strains showed only minor differences when penetration, excretion, tissue sequestration, or metabolism of [3H]JH III was measured. In contrast, when...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Alleles

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carrier Proteins

Share to Cytosol

Share to Drosophila melanogaster

Share to Genotype

Share to Insect Proteins

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 2107540
DOI: 10.1073/pnas.87.6.2072
PMCID: PMC53628

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resistance to juvenile hormone and an insect growth regulator in Drosophila is associated with an altered cytosolic juvenile hormone-binding protein.PMID 2107540Read ↗

Wide mutational spectrum of a gene involved in hormone action and insecticide resistance in Drosophila melanogaster.Semantic proximity Read ↗

Juvenile hormone involvement in Drosophila melanogaster male reproduction as suggested by the Methoprene-tolerant(27) mutant phenotype.Semantic proximity Read ↗

Genetic evidence that mutants of the methoprene-tolerant gene of Drosophila melanogaster are null mutants.Semantic proximity Read ↗

Ligand-binding properties of a juvenile hormone receptor, Methoprene-tolerant.Semantic proximity Read ↗

Molecular analysis of the Methoprene-tolerant gene region of Drosophila melanogaster.Semantic proximity Read ↗

The competitive ability and fitness components of the Methoprene-tolerant (Met) Drosophila mutant resistant to juvenile hormone analog insecticides.Semantic proximity Read ↗

A juvenile hormone agonist reveals distinct developmental pathways mediated by ecdysone-inducible broad complex transcription factors.Semantic proximity Read ↗

Transcription‐inducing activity of natural and synthetic juvenile hormone agonists through the Drosophila Methoprene‐tolerant proteinSemantic proximity Read ↗

Interaction between hormonal signaling pathways in Drosophila melanogaster as revealed by genetic interaction between methoprene-tolerant and broad-complex.Semantic proximity Read ↗

A mutation in the receptor Methoprene-tolerant alters juvenile hormone response in insects and crustaceans.Semantic proximity Read ↗

Pleiotropic effects of methoprene-tolerant (Met), a gene involved in juvenile hormone metabolism, on life history traits in Drosophila melanogaster.Semantic proximity Read ↗

Knockout of juvenile hormone receptor, Methoprene-tolerant, induces black larval phenotype in the yellow fever mosquito, Aedes aegyptiSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.