Article
The α7 nicotinic acetylcholine receptor and the acute stress response: maternal genotype determines offspring phenotype.
Physiology & behavior - 3 Aug 2011
Sinkus Melissa L, Wamboldt Marianne Z, Barton Amanda, Fingerlin Tasha E, Laudenslager Mark L, Leonard Sherry
Abstract excerpt
α7 Nicotinic acetylcholine receptors (α7nAchRs) modulate immune activation by suppressing production of pro-inflammatory cytokines in peripheral immune cells. α7nAchRs also modulate inhibitory output in the hippocampus, which provides input to key circuits of the HPA axis. Therefore, the α7 nicot...
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