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Article

Irradiation-induced p53 expression is attenuated in cells with NQO1 C465T polymorphism.

Journal of medical and dental sciences - 1 Jun 2010

Sato Masaki, Takagi Masatoshi, Mizutani Shuki

Abstract excerpt

NAD(P)H:quinone acceptor oxidoreductase (NQO) 1 polymorphism is associated with various hematological malignancies, especially infant leukemia or therapy-related leukemias, which involve the rearrangement of mixed lineage leukemia (MLL) gene. Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines (EBV-LCLs) with either of 2 well known polymorphic variations of C609T and C465T were selected from our...

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Identifiers

PMID: 21073132

Genes

NQO1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Irradiation-induced p53 expression is attenuated in cells with NQO1 C465T polymorphism.PMID 21073132Read ↗

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Effects of the NQO1 609C>T polymorphism on leukemia susceptibility: evidence from a meta-analysis.Semantic proximity Read ↗

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