Analysis of autosomal dosage compensation involving the alcohol dehydrogenase locus in Drosophila melanogaster.

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Article

Analysis of autosomal dosage compensation involving the alcohol dehydrogenase locus in Drosophila melanogaster.

Genetics - 1 Mar 1990

Birchler J A, Hiebert J C, Paigen K

Abstract excerpt

An example of autosomal dosage compensation involving the expression of the alcohol dehydrogenase (Adh) locus is described. Flies trisomic for a quarter of the length of the left arm of chromosome two, including Adh, have diploid levels of enzyme activity and alcohol dehydrogenase messenger RNA....

Topics

Alcohol Dehydrogenase
Animals
Chromosomes
Cloning, Molecular
DNA
Diploidy
Dosage Compensation, Genetic
Drosophila melanogaster
Female
Gene Expression Regulation, Enzymologic
Genes
Male
Phenotype
Promoter Regions, Genetic
RNA, Messenger
Transcription, Genetic
Translocation, Genetic
Trisomy

Source

Open in PubMed Open full text

Identifiers

PMID: 2107122
PMCID: PMC1203960

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2107122-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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