Article
Complexity in evolved regulatory variation for alcohol dehydrogenase genes in Hawaiian Drosophila.
Journal of molecular evolution - 1 Mar 1991
Fang X M, Wu C Y, Brennan M D
Abstract excerpt
The alcohol dehydrogenase gene (Adh gene) of Drosophila affinidisjuncta is expressed at a higher level in the larval midgut and Malpighian tubules than the homologous gene from Drosophila hawaiiensis. This study analyzed the cis-acting sequences responsible for these regulatory differences in larval tissues of Drosophila melanogaster transformants. A series of 10 chimeric and deleted Adh genes was introduced into...
Topics
- Alcohol Dehydrogenase
- Animals
- Biological Evolution
- DNA Transposable Elements
- Drosophila
- Electrophoresis, Polyacrylamide Gel
- Enhancer Elements, Genetic
- Gene Expression Regulation
- Genetic Variation
- Larva
- Promoter Regions, Genetic
