Article
Apolipoprotein AIMilano. Partial lecithin:cholesterol acyltransferase deficiency due to low levels of a functional enzyme.
Biochimica et biophysica acta - 12 Mar 1990
Franceschini G, Baio M, Calabresi L, Sirtori C R, Cheung M C
Abstract excerpt
The cholesterol esterification process was analyzed in 19 carriers of the apolipoprotein AIMilano (AIM) variant and in 19 age-sex matched controls by measuring lecithin:cholesterol acyltransferase (LCAT) mass, activity (i.e., cholesterol esterification with a standard proteoliposome substrate) and cholesterol esterification rate (i.e., cholesterol esterification in the presence of the endogenous substrate). The...
Topics
- Adolescent
- Adult
- Apolipoprotein A-I
- Apolipoproteins A
- Child
- Cholesterol Esters
- Genetic Variation
- Humans
- Hypolipoproteinemias
- Lecithin Cholesterol Acyltransferase Deficiency
- Lipoproteins, HDL