Article
Mutational and gene dosage analysis of calcium-activated potassium channels in Drosophila: correlation of micro- and macroscopic currents.
Neuron - 1 Feb 1990
Komatsu A, Singh S, Rathe P, Wu C F
Abstract excerpt
In Drosophila, two Ca2(+)-activated K+ currents, ICF and ICS, have previously been distinguished in conventional voltage clamp experiments. The slowpoke (slo) mutation eliminates ICF specifically. We report that in patch clamp recordings a single-channel Ca2(+)-activated K+ current is readily distinguished from other channel activities in normal larval muscle membrane, whereas no such current is observed in slo...
Topics
- Animals
- Calcium
- Drosophila melanogaster
- Electric Conductivity
- Genes
- Mutation
- Potassium Channels