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Article

Dependency of phenprocoumon dosage on polymorphisms in the VKORC1, CYP2C9, and CYP4F2 genes.

Pharmacogenetics and genomics - 1 Jan 2011

Teichert Martina, Eijgelsheim Mark, Uitterlinden Andrė G, Buhre Peter N, Hofman Albert, De Smet Peter A G M, Visser Loes E, Stricker Bruno H Ch

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) on warfarin and acenocoumarol showed that interindividual dosage variation is mainly associated with single nucleotide polymorphisms (SNPs) in VKORC1 and to a lesser extent in CYP2C9 and CYP4F2. For phenprocoumon dosage, the genes encoding CYP3A4...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21063236
DOI: 10.1097/FPC.0b013e32834154fb

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21063236-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Dependency of phenprocoumon dosage on polymorphisms in the VKORC1, CYP2C9, and CYP4F2 genes.PMID 21063236Read ↗

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Genetic determinants of acenocoumarol and phenprocoumon maintenance dose requirements.Semantic proximity Read ↗

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