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Article

Clusterin is epigenetically regulated in prostate cancer

22 Jul 2008

Abstract excerpt

Lack of good models has complicated investigations on the mechanisms of prostate cancer. By far, the most commonly used transgenic mouse model of prostate cancer is TRAMP, which, however, has not been fully characterized for genetic and epigenetic aberrations. Here, we screened TRAMP-derived C2 cell line for the alterations using different microarray approaches, and compared it to human prostate cancer. TRAMP-C2...

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PMID: 18649357
DOI: 10.1002/ijc.23658

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