Article
PADI4 polymorphism predisposes male smokers to rheumatoid arthritis.
Annals of the rheumatic diseases - 1 Mar 2011
Kochi Yuta, Thabet Mohamed M, Suzuki Akari, Okada Yukinori, Daha Nina A, Toes René E M, Huizinga Tom W J, Myouzen Keiko, Kubo Michiaki, Yamada Ryo, Nakamura Yusuke, Yamamoto Kazuhiko
Abstract excerpt
OBJECTIVE: To elucidate the differential role of peptidyl arginine deiminase 4 (PADI4) polymorphism in rheumatoid arthritis (RA) between Asian and European populations, possible gene-environmental interactions among the PADI4 polymorphism, sex and smoking status were analysed. METHODS: Three independent sets of case-control samples were genotyped for single-nucleotide polymorphisms in PADI4; Japanese samples...
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