Article
A genome-wide association scan on estrogen receptor-negative breast cancer.
Breast cancer research : BCR - 1 Jan 2010
Li Jingmei, Humphreys Keith, Darabi Hatef, Rosin Gustaf, Hannelius Ulf, Heikkinen Tuomas, Aittomäki Kristiina, Blomqvist Carl, Pharoah Paul Dp, Dunning Alison M, Ahmed Shahana, Hooning Maartje J, Hollestelle Antoinette, Oldenburg Rogier A, Alfredsson Lars, Palotie Aarno, Peltonen-Palotie Leena, Irwanto Astrid, Low Hui Qi, Teoh Garrett Hk, Thalamuthu Anbupalam, Kere Juha, D'Amato Mauro, Easton Douglas F, Nevanlinna Heli, Liu Jianjun, Czene Kamila, Hall Per
Abstract excerpt
INTRODUCTION: Breast cancer is a heterogeneous disease and may be characterized on the basis of whether estrogen receptors (ER) are expressed in the tumour cells. ER status of breast cancer is important clinically, and is used both as a prognostic indicator and treatment predictor. In this study, we focused on identifying genetic markers associated with ER-negative breast cancer risk. METHODS: We conducted a...
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