GWAS in the SIGNAL/PHARE clinical cohort restricts the association between the FGFR2 locus and estrogen receptor status to HER2-negative breast cancer patients.

doi:10.18632/oncotarget.12669

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GWAS in the SIGNAL/PHARE clinical cohort restricts the association between the FGFR2 locus and estrogen receptor status to HER2-negative breast cancer patients.

Oncotarget - 22 Nov 2016

Cox David G, Curtit Elsa, Romieu Gilles, Fumoleau Pierre, Rios Maria, Bonnefoi Hervé, Bachelot Thomas, Soulié Patrick, Jouannaud Christelle, Bourgeois Hugues, Petit Thierry, Tennevet Isabelle, Assouline David, Mathieu Marie-Christine, Jacquin Jean-Philippe, Lavau-Denes Sandrine, Darut-Jouve Ariane, Ferrero Jean-Marc, Tarpin Carole, Lévy Christelle, Delecroix Valérie, Trillet-Lenoir Véronique, Cojocarasu Oana, Meunier Jérôme, Pierga Jean-Yves, Faure-Mercier Céline, Blanché Hélène, Sahbatou Mourad, Boland Anne, Bacq Delphine, Besse Céline, Deleuze Jean-François, Pauporté Iris, Thomas Gilles, Pivot Xavier

Abstract excerpt

Genetic polymorphisms are associated with breast cancer risk. Clinical and epidemiological observations suggest that clinical characteristics of breast cancer, such as estrogen receptor or HER2 status, are also influenced by hereditary factors. To identify genetic variants associated with pathological characteristics of breast cancer patients, a Genome Wide Association Study was performed in a cohort of 9365...

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PMID: 27764800
DOI: 10.18632/oncotarget.12669
PMCID: PMC5363591

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FGFR2

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