Article
Immunogenicity and immunomodulatory properties of umbilical cord lining mesenchymal stem cells.
Cell transplantation - 1 Jan 2011
Deuse Tobias, Stubbendorff Mandy, Tang-Quan Karis, Phillips Neil, Kay Mark A, Eiermann Thomas, Phan Thang T, Volk Hans-Dieter, Reichenspurner Hermann, Robbins Robert C, Schrepfer Sonja
Abstract excerpt
We here present an immunologic head-to-head comparison between human umbilical cord lining mesenchymal stem cells (clMSCs) and adult bone marrow MSCs (bmMSCs) from patients >65 years of age. clMSCs had significantly lower HLA class I expression, higher production of tolerogenic TGF-β and IL-10, and showed significantly faster proliferation. In vitro activation of allogeneic lymphocytes and xenogeneic in vivo...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
