Article
Epigenetic change in e-cardherin and COX-2 to predict chronic periodontitis
4 Nov 2010
Abstract excerpt
BACKGROUND: DNA methylation of certain genes frequently occurs in neoplastic cells. Although the cause remains unknown, many genes have been identified with such atypical methylation in neoplastic cells. The hypermethylation of E-Cadherin and Cyclooxygenase 2 (COX-2) in chronic inflammation such as chronic periodontitis may demonstrate mild lesion/mutation epigenetic level. This study compares the...
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