Article
SUMO1 as a candidate gene for non-syndromic cleft lip with or without cleft palate: no evidence for the involvement of common or rare variants in Central European patients.
International journal of pediatric otorhinolaryngology - 1 Jan 2011
de Assis Nilma Almeida, Nowak Stefanie, Ludwig Kerstin U, Reutter Heiko, Vollmer Jennifer, Heilmann Stefanie, Kluck Nadine, Lauster Carola, Braumann Bert, Reich Rudolf H, Hemprich Alexander, Knapp Michael, Wienker Thomas F, Kramer Franz-Josef, Hoffmann Per, Nöthen Markus M, Mangold Elisabeth
Abstract excerpt
OBJECTIVE: Studies in mice and humans have suggested that SUMO1, which codes for the small ubiquitin-related modifier 1 (SUMO1), is a promising candidate gene for non-syndromic cleft lip with or without cleft palate (NSCL/P). To investigate the possible involvement of this gene in NSCL/P patients...
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