Article
FcγR polymorphisms and clinical outcome in colorectal cancer patients receiving passive or active antibody treatment.
International journal of oncology - 1 Dec 2010
Wang Biyun, Kokhaei Parviz, Mellstedt Håkan, Liljefors Maria
Abstract excerpt
Fcγ receptors (FcγRs) on effector cells are of importance for mediating antibody-dependent cellular cytotoxicity (ADCC). FcγRIIIa158valine (V)/phenylalanine (F) and FcγRIIa131histidine (H)/arginine(R) polymorphisms have been shown to relate to prognosis in antibody-treated patients. The aim of th...
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