Article
Phenotypic and genetic variation in leptin as determinants of weight regain.
International journal of obesity (2005) - 1 Jun 2011
Erez G, Tirosh A, Rudich A, Meiner V, Schwarzfuchs D, Sharon N, Shpitzen S, Blüher M, Stumvoll M, Thiery J, Fiedler G M, Friedlander Y, Leiterstdorf E, Shai I
Abstract excerpt
AIMS: Over 75% of obese subjects fail to maintain their weight following weight loss interventions. We aimed to identify phenotypic and genetic markers associated with weight maintenance/regain following a dietary intervention. SUBJECTS AND METHODS: In the 2-year Dietary Intervention Randomized Controlled Trial, we assessed potential predictors for weight changes during the 'weight loss phase' (0-6 months) and...
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