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Differential mechanisms affecting weight loss and weight loss maintenance.

Nature metabolism - 1 Aug 2023

Rosenbaum Michael, Foster Gary

Abstract excerpt

In most lifestyle, pharmacological and surgical interventions, weight loss occurs over an approximately 6- to 9-month period and is followed by a weight plateau and then weight regain. Overall, only about 15% of individuals can sustain a 10% or greater non-surgical, non-pharmacological, weight loss. A key question is the degree to which the genotypes, phenotypes and environmental correlates of success in weight...

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PMID: 37612402
DOI: 10.1038/s42255-023-00864-1

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