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Article

Genome-wide identification of Streptococcus pneumoniae genes essential for bacterial replication during experimental meningitis.

Infection and immunity - 1 Jan 2011

Molzen T E, Burghout P, Bootsma H J, Brandt C T, van der Gaast-de Jongh Christa E, Eleveld M J, Verbeek M M, Frimodt-Møller N, Østergaard C, Hermans P W M

Abstract excerpt

Meningitis is the most serious of invasive infections caused by the Gram-positive bacterium Streptococcus pneumoniae. Vaccines protect only against a limited number of serotypes, and evolving bacterial resistance to antimicrobials impedes treatment. Further insight into the molecular pathogenesis...

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Identifiers

PMID: 21041497
DOI: 10.1128/IAI.00631-10
PMCID: PMC3019918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21041497-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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