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Article

Normal red blood cells partially decrease diepoxybutane-induced chromosome breakage in cultured lymphocytes from Fanconi anaemia patients.

Cell proliferation - 1 Dec 2010

Porto B, Sousa R, Malheiro I, Gaspar J, Rueff J, Gonçalves C, Barbot J

Abstract excerpt

OBJECTIVES: Fanconi anaemia (FA) is a cancer-prone chromosome instability syndrome characterized by hypersensitivity to DNA cross-linking agents, such as diepoxybutane (DEB). Previous studies have shown that normal red blood cells (RBC) can protect cultured lymphocytes against chromosomal breaks...

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Identifiers

PMID: 21039995
DOI: 10.1111/j.1365-2184.2010.00706.x
PMCID: PMC6496188

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21039995-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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