Article
Somatic stem cells express Piwi and Vasa genes in an adult ctenophore: ancient association of "germline genes" with stemness.
Developmental biology - 1 Feb 2011
Alié Alexandre, Leclère Lucas, Jager Muriel, Dayraud Cyrielle, Chang Patrick, Le Guyader Hervé, Quéinnec Eric, Manuel Michaël
Abstract excerpt
Stem cells are essential for animal development and adult tissue homeostasis, and the quest for an ancestral gene fingerprint of stemness is a major challenge for evolutionary developmental biology. Recent studies have indicated that a series of genes, including the transposon silencer Piwi and the translational activator Vasa, specifically involved in germline determination and maintenance in classical...
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