[Caloric restriction increases life span in sterile and non-sterile D. melanogaster females: systems analysis].

Abstract excerpt

Experiments show that moderate caloric restriction in normal (non-sterile) fruit flies results in the increase of life span. It has been found recently that life span increases under caloric restriction also in sterile Drosophila females. This fact was explained by remodeling of metabolism due to insulin signaling. In this paper a hypothesis is put forward that under caloric restriction in the organism, the...

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