Article
Human-readable rule generator for integrating amino scid sequence information and stability of mutant proteins.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Huang Liang-Tsung, Lai Lien-Fu, Gromiha M Michael
Abstract excerpt
Most of the bioinformatics tools developed for predicting mutant protein stability appear as a black box and the relationship between amino acid sequence/structure and stability is hidden to the users. We have addressed this problem and developed a human-readable rule generator for integrating the knowledge of amino acid sequence and experimental stability change upon single mutation. Using information about the...
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