Article
The contribution of inherited predisposition to cancer incidence.
Cancer surveys - 1 Jan 1990
Easton D, Peto J
Abstract excerpt
Only a small proportion of cancers, arising in inherited syndromes such as polyposis coli, have an unequivocally inherited basis. Nevertheless, most common cancers show familial clustering, much of which may be due to inherited predisposition. If so, there may be wide variation in genetic susceptibility to common cancers. The precise models of susceptibility are unclear, but for ovarian cancer and breast cancer...
Topics
- Disease Susceptibility
- Family
- Genetic Linkage
- Humans
- Incidence
- Neoplasms
- Phenotype