Article
Increased susceptibility of malaria-infected variant erythrocytes to the mononuclear phagocyte system.
Blood cells - 1 Jan 1990
Yuthavong Y, Bunyaratvej A, Kamchonwongpaisan S
Abstract excerpt
The interactions of the mononuclear phagocyte system with Plasmodium falciparum-infected genetically variant erythrocytes may result in a significant protection for the host. Infected hemoglobin (Hb) EE and Hb EA erythrocytes are more susceptible to phagocytosis by monocytes than are infected Hb AA erythrocytes. The increased susceptibility to phagocytosis of infected erythrocytes was also found for a number of...
Topics
- Animals
- Erythrocytes
- Genetic Variation
- Hemoglobins, Abnormal
- Humans
- Macrophages
- Malaria
- Monocytes
- Phagocytosis
- Plasmodium falciparum
