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Article

Brief communication: Resistance to Falciparum malaria in alpha-thalassemia, oxidative stress, and hemoglobin oxidation.

American journal of physical anthropology - 1 Jun 1999

Destro-Bisol G, D'Aloja E, Spedini G, Scatena R, Giardina B, Pascali V

Abstract excerpt

A recent survey conducted on Vanuatu Island suggests that resistance to Plasmodium falciparum in alpha-thalassemic individuals may have an immunological basis. This study is important since it seems to undermine the current idea that red-cell genetic defects give protection against falciparum malaria by reducing intraerythrocytic growth and development of the parasite. However, the mechanisms underlying these...

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Identifiers

PMID: 10378464
DOI: 10.1002/(SICI)1096-8644(199906)109:2<269::AID-AJPA11>3.0.CO;2-#

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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