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Article

Innate resistance to malaria: the intraerythrocytic cycle.

Blood cells - 1 Jan 1990

Nagel R L

Abstract excerpt

The human innate resistance to P. falciparum malaria is based on genetic features that affect several stages of the intraerythrocytic cycle of the plasmodia. HbS, HbE and alpha and beta thalassemia (in addition to G-6PD deficiency) are protective to the carriers, because they inhibit the intraerythrocytic growth period, and in the case of AS red cells, in addition, parasitosis make them detectable expeditiously...

Topics

Animals
Erythrocytes
Hemoglobin E
Hemoglobin, Sickle
Hemoglobinopathies
Humans
Immunity, Innate
Malaria
Mutation
Plasmodium falciparum
Thalassemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2257317

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2257317-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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