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Article

CDKN2BAS is associated with periodontitis in different European populations and is activated by bacterial infection.

Journal of medical genetics - 1 Jan 2011

Schaefer Arne S, Richter Gesa M, Dommisch Henrik, Reinartz Markus, Nothnagel Michael, Noack Barbara, Laine Marja L, Folwaczny Mathias, Groessner-Schreiber Birte, Loos Bruno G, Jepsen Søren, Schreiber Stefan

Abstract excerpt

Epidemiological studies have indicated a relationship between coronary heart disease (CHD) and periodontitis. Recently, CDKN2BAS was reported as a shared genetic risk factor of CHD and aggressive periodontitis (AgP), but the causative variant has remained unknown. To identify and validate risk variants in different European populations, we first explored 150 kb of the genetic region of CDKN2BAS including the...

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Share to Aggressive Periodontitis
Share to Chronic Periodontitis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase 4

Share to Cyclin-Dependent Kinase Inhibitor p15

Share to Gingiva

Share to Periodontitis

Share to Porphyromonas gingivalis

Share to RNA, Antisense

Source

Identifiers

PMID: 20978019
DOI: 10.1136/jmg.2010.078998

Genes

CDK4
HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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