Article
Salmonella enterica serovar Typhimurium binds to HeLa cells via Fim-mediated reversible adhesion and irreversible type three secretion system 1-mediated docking.
Infection and immunity - 1 Jan 2011
Misselwitz Benjamin, Kreibich Saskia K, Rout Samuel, Stecher Bärbel, Periaswamy Balamurugan, Hardt Wolf-Dietrich
Abstract excerpt
The food-borne pathogen Salmonella enterica serovar Typhimurium invades mammalian epithelial cells. This multistep process comprises bacterial binding to the host cell, activation of the Salmonella type three secretion system 1 (T1), injection of effector proteins, triggering of host cell actin rearrangements, and S. Typhimurium entry. While the latter steps are well understood, much less is known about the...
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